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June 8, 2019

An award certificate suitable for framing

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It came in the mail last week, already framed.

June 8, 2019 at 04:01 PM | Permalink | Comments (3)

Helpful Hints from joeeze: A bread knife makes short work of styrofoam

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Up to yesterday I did the best I could cutting styrofoam for my various projects using a utility knife.

Then it occurred to me to try my trusty bread knife (top).

Bingo — fantastic results.

Not only for sheet and block styrofoam but also for 6"-diameter rolls, where the bread knife — with its 10"-long blade — is paradoxically way more precise and controllable than a short-bladed utility knife (below),

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my former tool of choice, which makes only a 1"-deep incision and therefore requires many circuits to cut all the way through a thick roll of styrofoam.

June 8, 2019 at 02:01 PM | Permalink | Comments (0)

Why We Sigh

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[Caption for photo above: On each side of the brain stem, a fluorescent-green marker illuminates the network of 200 neurons that control the sighing reflex.]

From the Wall Street Journal:

Shakespeare cautioned ladies to "sigh no more" over unfaithful lovers. But scientists say that's easier said than done.

Exploring the biology of the sigh, researchers at the University of California, Los Angeles and Stanford University said they have pinpointed the neural structures that tell the brain when and how to sigh.

The researchers said their findings, reported [last week] in the journal Nature, support the theory that sighing isn't just an emotional outlet; it's a vital biological process necessary for maintaining overall health.

Researchers are just starting to grasp why and how we sigh, and what happens when we don't.

In the brain, sighs stimulate neural activity, signal changes in behavior and reset breathing rates.

In the respiratory system, sighs clear airways and help the lungs absorb oxygen. Too much or too little sighing can lead to neurological diseases, scientists say.

"A sigh is the ultimate arousal" for the brain, said Nino Ramirez, director of the Center for Integrative Brain Research at the Seattle Children’s Research Institute, who wasn't involved in the new study.

Humans breathe "restorative sighs" about once every five minutes, often without noticing.

The double inhalation activates the brain's cortex, the portion responsible for emotions, speech, recognition, reasoning and other higher functions, Dr. Ramirez said.

In the lungs, tiny air sacs called alveoli absorb oxygen and exchange it with the body's carbon dioxide, which is eliminated through exhalation.

During periods of normal breathing, the alveoli gradually deflate "like wet balloons," said Jack Feldman, distinguished professor of neurobiology at the University of California Los Angeles' David Geffen School of Medicine and co-author of the new paper.

Collapsed alveoli can't absorb enough oxygen, and regular breaths are too weak to inflate them. Sighs — triggered when the brain senses inadequate oxygen — pop the sacs open again.

In the new research, a team led by Dr. Feldman and Mark Krasnow, a professor of biochemistry at the Stanford University School of Medicine, screened more than 19,000 gene expressions in rats' brain cells.

They identified two bundles of neurons that produced two particular neuropeptides, chemicals that let brain cells talk to one another, that they thought could be associated with sighing.

To test the theory, the team injected the neuropeptides into another group of neurons in the rats' brains called the Pre-Bötzinger complex, which sets the breathing rate and determines the types of breaths.

Right away, the rats' normal sighing rate switched into overdrive, jumping from about 40 to 400 times per hour.

When the researchers removed the neuropeptides, the rats stopped sighing altogether.

"It was immediate and dramatic," Dr. Krasnow said, adding that the experiment didn't change the rats' normal breathing.

Many neurological conditions, such as anxiety, sleep apnea and sudden infant death syndrome, are linked to improper breathing.

For example, people with panic disorders may sigh too much, overstimulating the brain's cortex and leading to problems like insomnia.

"There are a number of syndromes characterized by excess sighing. Now that we know which neurons are linked to sighing, and which neuropeptides trigger them, we can reduce the number and the rate of sighs," Dr. Krasnow said.

In the future, Dr. Krasnow said, drugs that increase sighing could be developed for hospital patients who would otherwise need to go on ventilators to breathe. The finding could also mean that other neurons within the brain's breathing circuitry may control yawning, coughing, laughing, or gasping.

"The paper shows one pathway," said Dr. Ramirez, "but I think there will be more. Knowing the pathways will help us unravel the sigh."

June 8, 2019 at 12:01 PM | Permalink | Comments (0)

The Great Lakes: An Ojibwe Perspective

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The toponyms on this map are here.

[via Nag on the Lake]

June 8, 2019 at 10:01 AM | Permalink | Comments (0)

Legends Ultimate Arcade Cabinet

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From Ars Technica:

MAME (Multiple Arcade Machine Emulator) for the masses?

Right now, I can almost hear scores of a certain breed of commenter typing out that this kind of machine is pointless when you can just build your own MAME cabinet and load it with thousands of ROM files yourself.

But even with pre-cut parts and pre-compiled emulators, building your own cabinet from scratch requires a level of tinkering that not every nostalgic gamer has the time or inclination for.

The Legends Ultimate could provide a simple, cheap, no-nonsense entry point for retro arcade fans who just want to play a wide selection of classics in their original form-factor without taking on a do-it-yourself project (plus the officially licensed games are actually legal and provide money to the rights-holders, for those who care about such things).

This is far from the first "multicade" to hit the market or aim for home users. But this "all-in-one" cabinet, with pre-orders planned to start in July, differentiates itself in part with a console-level suggested retail price: $599 for a the full-sized 66" cabinet, or $399 for a "compact" 44" tall version. That's a huge step down in cost from existing options that can easily cost thousands of dollars for a full-sized upright cabinet.

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AtGames, the maker, doesn't exactly have the best reputation in the retro games community — its plug-and-play consoles tend to have a bit of a slapdash quality to them.

And there are still a lot of unanswered questions regarding the Legends Ultimate's build quality, emulation, game expansion costs, and more that we hope to get answered at an E3 demo next month.

For now, though, we're at least intrigued by what seems like an ambitious effort to build an all-in-one, expandable retro gaming cabinet that could thread the needle between authenticity and affordability.

Honestly, we're surprised no one has tried something similar before now.

The press release promises Bluetooth compatibility and built-in WiFi hardware, enabling leaderboards, tournaments, network play, and game downloads, along with "cloud game streaming."

Some of the promised "200 to 400" games revealed for the Arcade Legends cabinet include:

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Apply within.

June 8, 2019 at 08:01 AM | Permalink | Comments (0)

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